https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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Applying solitary-molecule optical and AFM imaging and power-spectroscopy techniques, we request to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our study pursuits include things like:
You frequently get involved in conversations about science and faith. You have got also prepared a number of guides on the topic. Don’t you believe that in some unspecified time in the future We are going to know every thing Which God’s function are going to be above?
‘It had been just a make a difference of picking up a reserve on cell biology and starting to browse. I had originate from a entire world of ultra-superior vacuums, cryostats and quantum phenomena, and now I used to be Functioning at room temperature with molecular biology kits.
Non-equilibrium folding of particular person DNA molecules recaptured as many as a thousand periods in a very stable condition nanopore
2010, created a whole new way (‘wedging transfer’) to govern nanostructures; to start with report of DNA translocation through graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic buildings to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks which assess the basic position of spatial confinement with the molecular and cellular degree. Our assignments contain the following:
Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation
In 1993, for a young and eager affiliate professor at Delft College of Technologies, I had in the beginning focused the investigation endeavours of my ceesdekker.net group on measuring the electrical conductance of just one conducting-polymer molecule. Within just two years, we had designed a tool by which one wire of the phthalocyaninepolysiloxane polymer was related in between two carefully spaced steel nanoelectrodes.
one). The present–voltage curves confirmed considerable modulations with gate voltage, even at room temperature, which was in keeping with band bending inside a ~0.six eV bandgap semiconducting nanotube. These information also confirmed that the conductance may be modulated by six orders of magnitude by shifting the gate voltage. The results of this work — a area-temperature transistor made from an individual carbon nanotube molecule — were being revealed in Mother nature in Might 1998.
Screening pseudotopological and nontopological styles for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments
Lots of new phenomena have been found, and he and his research team established a number one place in this subject of study. Dekker and his research team discovered new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they had been the first to create a transistor based on one nanotube molecule.
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Last but not least, I'll briefly sketch many of our ideas to discover the creating of synthetic cells, especially our very first methods to ascertain synthetic cell division.